Objective To evaluate the damage to retinal function in patients receiving hydroxychloroquine （HCQ） by observing the changes in the retinal nerve fiber layer （RNFL）. Methods A retrospective study was performed on 30 patients with rheumatoid arthritis who were treated with HCQ therapy and 30 healthy people. Visual acuity， visual field and fundus examinations as well as optical coherence tomography （OCT） were compared between the two groups. Results Visual acuity， visual field and fundus examinations were normal. Decreases were noted with OCT. Conclusion OCT can detect early retinal toxicity due to hydroxychloroquine.
胡赛静,毛崇溶. 应用OCT观察羟氯喹对视网膜的早期影响[J]. 中华眼视光学与视觉科学杂志, 2015, 17(3): 181-183.
Hu Saijing,Mao Chongrong. Effect of hydroxychloroquine treatment on the retinal nerve fiber layer. Chinese Journal of Optometry Ophthalmology and Visual science, 2015, 17(3): 181-183. DOI: 10.3760/cma.j.issn.1674-845X.2015.03.012
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