Objective: To compare the visual quality of the Symfony extended range of vision intraocular lensand the Tecnis ZMBOO multifocal intraocular lens, which can provide a theoretical basis for clinical promotionand application. Method: This was a retrospective case control analysis. One hundred thirteen patients (113 eyes) with cataract, who underwent phacoemulsification and IOL implantation, were divided into two groups: 63 patients (63 eyes) who were prescribed Symfony extended range of vision intraocular lenses and 50 patients (50 eyes) who were prescribed Tecnis ZMBOO multifocal intraocular lenses. Far, intermediate, and near distance vision were tested at postoperative 3 months. A binocular defocus curve was plotted, contrast sensitivity wave front aberrations were measured and patients answered a questionnaire. Data from the two groups were statistically analyzed by t test. Results: There was no significant difference invisual acuity between the two groups at 3 months postoperatively. Near vision (33 cm) in the ZMBOO group was superior to the Symfony group, and the difference was statistically significant (t=6.641, P=0.002). The intermediate-distance visual acuity (60 cm, 80 cm) of the Symfony group was superior to that of the ZMBOO group, and the difference was statistically significant (t=3.942, P=0.020; t=4.247; P=0.011). Three months after surgery, the defocus curve of the two groups showed that the Symfony group tended to be stable between +0.5 D and -2.5 D, and vision was above 0.3 LogMAR, forming a platform stage, and was more consistently superior to that of the ZMBOO group. The ZMBOO group showed a double peak, with a peak value of 0 D and -3.5 D. There were no statistically significant differences in spatial frequency contrast sensitivity between the two groups under visual acuity conditionsand visual acuity with glare three months after surgery. Under dark conditions, the contrast sensitivities for the spatial frequencies of the Symfony group were better than that of ZMBOO group at 3.0 c·d-1, 6.0 c·d-1, and 12.0 c·d-1, and the differences were statistically significant (t=8.246, P=0.013; t=10.831, P=0.006; t=6.246, P=0.027). Three months after surgery, the total aberrations, higher-order aberrations, and coma aberrations of the Symfony group were lower than that of the ZMBOO group, and the differences were statistically significant (t=3.302, P=0.035; t=9.495, P=0.010; t=5.310, P=0.018; t=4.259, P=0.024). There was no significant difference in total lower order aberrations, spherical aberrations and second-order astigmatism in the two groups. Conclusion: Symfony extended range of vision intraocular lenses can provide patients with good visual quality and continuous range of vision, while Tecnis ZMBOO multi-focus IOL is more suitable for near vision.
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