Abstract：Objective: To explore a practical system for precision prevention and control against coronavirus disease 2019 (COVID-19) for eye hospitals by emphasizing systematic and standardized virus RNA detection procedures. Methods: In this case series study, standardized virus RNA detection along with a routine blood test (BRT), C-reactive protein (CRP) and serum amyloid A (SAA) were included in preoperative screening test items for ocular surgical patients and to provide virus RNA detection for returning employees between 24 February 2020 and 2 March 2020. In addition, a questionnaire was designed to investigate the acceptability of nasopharyngeal swab sampling and the influence of virus RNA detection results on the mental status of the examinee. Results: Ninety-nine examination results showed a certain percentage of abnormal test results, among which 13 cases showed an increase in SAA, 12 cases showed a decrease in lymphocyte count (LYM) while 5 cases showed an increase, 1 case showed a decrease in white blood count (WBC) while 11 cases showed an increase, and 2 cases showed an increase in CRP. All cases tested negative for novel coronavirus (2019-nCoV) RNA detection, including examined patients and 33 employees of the Eye Hospital. 11.7% of respondents reported a low acceptance score for nasopharyngeal swab sampling. The proportion of the examinees with higher mental stress scores before and after the virus RNA detection test was 46.7% and 6.7%, respectively. Conclusions: The detection procedures can offer an objective basis for preoperative screening and differential diagnosis, while largely eliminating the possibility of transmission via asymptomatic infected individuals. On the other hand, the negative result of virus RNA detection is beneficial in adjusting a patient's preoperative psychological state and relieving the mental stress of medical staff during the epidemic.
Wei-jie Guan, Z Ni, YU HU, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med, DOI: 10.1056/NEJMoa2002032.
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Yanfang Jiang, Haifeng Wang, Yukun Chen, etc. Clinical Data on Hospital Environmental Hygiene Monitoring and Medical Staffs Protection during the Coronavirus Disease 2019 Outbreak. [J/OL]. medRxiv https://www.medrxiv.org/content/10.1101/202 0.02.25.20028043v1.full.pdf.
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