角膜塑形镜对角膜影响的研究现状与进展

doi:10.3760/cma.j.cn115909-20190307-00062

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摘要目前，角膜塑形镜控制近视的有效性已得到验证，但由于其紧贴角膜，可能会对角膜产生一定影响。首先，它会对中央区角膜产生一定的压力，这种压力会对镜片下的泪液流动造成影响，继而影响角膜的氧气和营养物质供给，角膜相对缺氧导致其抵抗力下降。此外，镜片磨损划伤角膜，清洁不彻底导致微生物聚集引起角膜病变，严重者将导致角膜感染。再者，角膜经过塑形后形状会发生一定的改变，厚度会产生变化，进而影响到角膜各层结构之间的作用力。最后，长期的压迫还将导致角膜神经发生改变，敏感性降低。角膜塑形镜对角膜的影响一直是研究的热点，现对此进行总结。

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关键词 ：角膜塑形镜, 角膜, 角膜生物力学, 角膜敏感性

Abstract：At present, the effectiveness of orthokeratology in controlling myopia has been demonstrated.However, because the lensis close to the cornea, it maybe have an effect on the cornea. First of all, it will exert a certain pressure on the middle region of the cornea.This pressure will affect the flow of tears under the lens, thereby affecting the supply of oxygen and nutrients to the cornea. The relative hypoxia of the cornea leads to a decline in immunity. In addition, lens abrasion scratches the cornea. Partial cleaning of the lens leads to microbial aggregation, causing corneal lesions or even corneal infection. Furthermore, the corneal shape will deform and the thickness will change after wearing, which will affect the force between the layers of the cornea. Finally, long-term compression will also lead to changes in the corneal nerves and reduced sensitivity.The influence of orthokeratology on the cornea has always been a hot topic. This review summarizes the influence of orthokeratology on the cornea.

Key words： orthokeratology cornea corneal biomechanical corneal sensitivity

收稿日期: 2019-03-07

通讯作者: 廖洪斐（ORCID：0000-0002-3592-8605），Email：drliaohongfei@126.com

引用本文:

廖洪君1 熊芬2 廖洪斐2. 角膜塑形镜对角膜影响的研究现状与进展[J]. 中华眼视光学与视觉科学杂志, 2020, 22(6): 476-480. Hongjun Liao1,Fen Xiong2,Hongfei Liao2. Current Situation and Progress of Orthokeratology's Influence on the Cornea. Chinese Journal of Optometry Ophthalmology and Visual science, 2020, 22(6): 476-480. DOI: 10.3760/cma.j.cn115909-20190307-00062

链接本文:

https://www.cjoovs.com/CN/ 10.3760/cma.j.cn115909-20190307-00062 或 https://www.cjoovs.com/CN/Y2020/V22/I6/476

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