Abstract：Corneal biomechanics has become a research hotspot in recent years. The deepening of research results in a new interdisciplinary-mechanobiology. Mechanobiology is a discipline to study the relationship between mechanics and biological processes in organism at cellular, molecular, and genetic levels through mechanical principles and methods. The cornea is in a complex mechanical environment under the intraocular pressure, and various diseases and surgeries can cause changes in its stress environment. Studying biological response of corneal tissues and cells to mechanical stimuli has very important scientific and clinical significance for understanding the physiological and pathological processes of the cornea and the diagnosis and treatment of corneal related diseases. This article comprehensively describes progress in corneal mechanobiology in recent years, in order to provide new research directions and ideas for the related corneal mechanobiology research.
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