Recent advancement in ophthalmic fundus imaging has already revolutionized the diagnosis and therapy of retinal disease. Currently available systems include color fundus image, red-free fundus images, fundus autofluorescence image (FAF), fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA) and spectral-domain optical coherence tomography (S-OCT). Comprehensive knowledge of the technical and clinical aspects of these current methods, with emphasis on the evaluation of appropriate diagnostic imaging information, would be of extreme importance in differentiating a variety of choroidal abnormalities and retinal diseases, and determining therapeutic strategies, as well as following the progression of the disease.