Objective To investigate the changes in the characteristics of anisometropia and stereopsis recovery in patients with refractive accommodative esotropia after receiving a refractive correction. Methods In this retrospective study， all patients with refractive accommodative esotropia with complete medical records were divided into groups based on the initial power of anisometropia [low （anisometropia≤1.0 D）， moderate （1.0 D<anisometropia<2.5 D） or high （anisometropia≥2.5 D）] and initial visual acuity （binocular vision balance or the amblyopic eye）. An independent samples t test， mixed linear model analysis and chi-square test was used for statistical analysis. Results After 6.8±2.8 years follow-up， 87（82.1%） patients had a lower degree of anisometropia， 14（13.2%） patients had a moderate degree of anisometropia， and 5（4.7%） patients had a high degree of anisometropia. ①The effect of the refractive correction on the initial binocular visual acuity showed a statistically significant improvement （t=9.787， P<0.05）； ②The influence of the initial degree of anisometropia on stereopsis recovery was statistically significant （χ2=18.785， P<0.01）； ③After wearing glasses， a decrease in the trend of the spherical equivalent was observed in the three anisometropia groups（F=142.913， P<0.01）. Conclusion In this study， a higher initial degree of anisometropia is correlated with a lower initial visual acuity and a poorer subsequent stereopsis. With an increase in the amount of time glasses are worn， the initial states of anisometropia tend to change toward a more balanced refraction.