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Chinese Journal of Optometry Ophthalmology and Visual science
 
2019 Vol.21 Issue.7
Published 2019-07-25
Case Report
Original Articles
Review
Original Articles
481 The Effect of Cycloplegia on the IOLMaster 700 and OA-2000 Biometry in Cataract Patients
Yuyu Zhao, Zhongxing Chen, Luting Pan, Qing Wang, Fan Zhang, Yun'e Zhao
Objective: To evaluate the effect of cycloplegiaon new ocular biometry measurements using the IOLMaster 700 and OA-2000 biometers and assess the differences and agreements between the two devices. Methods: In this prospective, comparative, observational study of ocular measurements on 133 cataracts, measurements of axial length (AL), mean keratometry (Km), anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT) and white-to-white (WTW) were performed by a single operator using the two devices before and after pupil dilation. The measurement order of the two devices was determined according to the random number table. A paired t-test was applied to evaluate the differences with and without cycloplegia on each device. Bland-Altman plots and a paired t-test were used to evaluate the agreements and differences between the two devices with and without cycloplegia. Results: Cycloplegia had no significant effect on AL or Km. However, ACD and CCT significantly increased by 0.06 mm and 2-3 μm post-cycloplegia on both devices. The IOLMaster 700 LT measurements significantly decreased by 0.01 mm (t=-6.26, P<0.001) and WTW increased by 0.12 mm (t=7.06, P<0.001) after pupil dilation. ACD measurements with OA-2000 were higher by 0.04 mm (t=-13.36, P<0.001; t=-15.08, P<0.001) and LT by 0.07 mm (t=-11.11, P<0.001; t=-8.42, P<0.001), which were statistically significant, compared to the IOLMaster 700 before and after pupil dilation, while CCT was smaller by 17 μm (t=30.55, P<0.001; t=28.80, P<0.001). The 95% limits of agreement in both devices were -0.79 to 0.81 mm pre-cycloplegia and -0.44 to 0.81 mm post-cycloplegia. All measurements had good agreements between the two devices, except for WTW. Conclusions: Cycloplegia affects ACD and CCT, but not AL or Km measurements. LT decreased and WTW increased on the IOLMaster 700 after pupil dilation. Generally, there is good agreement between the IOLMaster 700 and OA-2000, except for WTW. Thus, either can be used for the preoperative examination of cataracts.
2019 Vol. 21 (7): 481-487 [Abstract] ( 464 ) [HTML 1KB] [ PDF 706KB] ( 3238 )
488 Consistency of Corneal Thickness and Anterior Chamber Depth Measured by Pentacam and VX120
Qingwei Zhang, Changbin Zhai, Dongli Ma, Jing Zhang, Yuehua Zhou
Objective: To compare the consistency of central corneal thickness (CCT), minimum corneal thickness (MinCT) and anterior chamber depth (ACD) measured by Pentacam and VX120. Methods: In this case series study, 71 myopia patients with (142 eyes) who planned to receive refractive surgery were enrolled from the March 2018 to April 2018, in Beijing Tongren Hospital. All subjects were under CCT, MinCT, ACD measurement by Pentacam and VX120. Due to that data of both eyes were used, thus a Rosner-Glynn-Lee method was used to make correction. The clustered rank sign test was used to compare the measurements of different equipment. The intra-class correlation coefficient (ICC) and Bland-Altman 95% limits of agreement were used to measure the consistency of measurement of different equipment. Results: CCT, ACD measured by the VX120 was lower than Pentacam (Z=3.524, 7.446, all P<0.001). There was no statistical difference in the measurement of MinCT between VX120 and Pentacam (Z=0.679, P=0.497). The ICC of MinCT measured by VX120 and Pentacam was 0.9 and the Bland-Altman plot showed that 93.7% of the data were distributed within the confidence interval. The 95% limits of agreement of MinCT were -27.81 to 29.26 μm for these two devices. Conclusions: VX120 has a high consistency with Pentacam on the measurement of MinCT. However, the measurements acquired by VX120 should not be directly interchangeable with Pentacam measurements in clinical practice.
2019 Vol. 21 (7): 488-492 [Abstract] ( 410 ) [HTML 1KB] [ PDF 705KB] ( 2779 )
493 Community Survey of Low Vision in Two Communities of Beijing in China
Yanhong Zou, Qian Li, Shanshan Cui, Wei Jia, Xipu Liu
Objective: To investigate the visual function, major causes of visual impairment, vision-related quality of life and rehabilitation needs of low vision patients in two communities of Beijing. Methods: Visually disabled people registered in the Desheng community, Xicheng district and the Jiuxianqiao community, Chaoyang district in Beijing were included in this cross sectional epidemiological study from September 2013 to April 2015. Interviews, visual acuity tests, slit lamp examination, and funduscopy were performed. Vision-related quality of life, a questionnaire about living conditions and rehabilitation needs were recorded during home visits. Data were analyzed with a χ2 test, t test or rank-sum test. Logistic regression were used to identify the factors relevant to vision-related quality of life. Results: There were 388 visually disabled people registered in these two communities. One hundred fifty-one patients (39.0%) were visited and evaluated at home. Of the 151 participants, 110(74.3%) were identified as low vision according to the Bangkok-Madrid standard. Among them, 66 patients (60.0%) had a best corrected visual acuity for either eye that was lower than 0.05 or the residual visual field radius was less than 10°. The main causes for visual impairment were retinal or uveal diseases 55(50.0%), glaucoma 15(13.6%), or congenital or inherited diseases 15(13.6%). Their main rehabilitation needs were going outside by themselves and reading, which amounted to 81.8%. The average score for quality of life was 47.3±26.7 with a personal interview using the low vision quality-of-life questionnaire (LVQOL). No significant relationship was found between score and sex, age, or vision function among low vision patients. But for all participants, age and residual visual field were the main factors related to quality of life (P<0.001). Conclusions: Low vision people accounted for the major portion of visually disabled people in two Beijing communities. Their visual function is poor, and quality of life drops dramatically. The main causes of their visual impairments are irreversible eye diseases. They need the most help are going outside and reading.
2019 Vol. 21 (7): 493-498 [Abstract] ( 404 ) [HTML 1KB] [ PDF 687KB] ( 2449 )
499 Characteristics of Angle Kappa in Cataract Patients and Changes under Photopic and Mesopic Conditions
Mengqiong Li, Zuhong Mao, Guangbin Zhang
Objective: To observe the characteristics and rule of change of the angle Kappa in cataract patients under photopic and mesopic conditions. Methods: In this case series study, a total of 788 eyes in 394 cataract patients receiving cataract surgery in the Affiliated Eye Center of Xiamen University were selected from May 2016 to October 2017. All patients were examined by OPD-Scan Ⅲ. The collected data included the clinical data of patients (such as age, gender, ocular history and surgical history), as well as preoperative biometric data, including mean corneal keratometry (mean K), and corneal spherical aberration (CSA), white-to-white distance (WTW), photopic pupil diameter (Photopic), mesopic pupil diameter (Mesopic), distance and angle of photopic angle Kappa (PDist@Angle), distance and angle of mesopic angle Kappa (MDist@Angle), and distance and angle from the mesopic pupil center to the photopic pupil center (MPDist@Angle) and so on. Specific tests included Rank sum test, Chi-square test, and multiple regression statistical analysis. Results: There were no significant differences in the biometric data, such as mean K, MPDist, PDist, WTW, and CSA between the two eyes (P>0.05), but the differences in photopic pupil diameter, mesopic pupil diameter, and MDist between the two eyes were statistically significant (Z=2.276, 3.284, 2.388, all P<0.05). The angle Kappa for most patients in the two eyes under photopic or mesopic conditions was positive, and the pupil center usually shifted inferotemporally when the illumination was changed from photopic to mesopic. The clinical and biometric data for both eyes were analyzed by multiple regression analysis with MPDist. The regression equation of the right eye was MPDist=0.033+0.505×MDist+0.041×CSA-0.319×PDist (F=45.0, P<0.001), while that of the left eye was MPDist=-0.002+0.547×MDist+0.013×Mesopic-0.350×PDist (F=61.6, P<0.001). Conclusions: In cataract patients, most eyes have a positive angle Kappa, and the variation in pupil size under different illuminations affect the size of the angle Kappa. Large differences can be detected in photopic pupil size, mesopic pupil size and the direction and shift of the pupil center during photopic and mesopic alternation. There was a linear regression relationship between MPDist changes and PDist, MDist, Mesopic, CSA. Among them, MPDist of both eyes were negatively correlated with PDist, and MDist of both eyes had relatively larger influence on MPDist changes.
2019 Vol. 21 (7): 499-506 [Abstract] ( 446 ) [HTML 1KB] [ PDF 1696KB] ( 3789 )
507 Comparison of the Clinical Effects of Bromfenac Sodium and Fluorometholone after LASEK Surgery
Kun Yang, Weili Geng
Objective: To compare the effectiveness of bromfenac sodium and fluorometholone eye drops on relieving corneal irritation and its safety in clinical applications after laser epithelial keratomileusis (LASEK) surgery. Methods: This was a prospective randomized, controlled study. A total of 60 patients (120 eyes) who underwent LASEK surgery from April 2017 to February 2018 in Tianjin Eye Hosptial were divided randomly into a bromfenac sodium group and a fluorometholone group according to the random number table, 30 patients (60 eyes) were included in each group. In the first week after the surgery, the bromfenac sodium group was given 0.1% bromfenac sodium eye drops twice a day, and then from the second week, this eye drops changed to 4 times per day for 1 month and 2 times per day in the following month. While the fluorometholone group was given 0.3% sodium hyaluronate eye drops twice a day in the first week after the surgery, then the eye drops changed to 0.1% fluorometholone by giving 4 times per day, which was gradually tapered in every month to the end. Corneal irritation and epithelial healing were evaluated at 1 d, 2 d, 3 d and 5 d after surgery. Examinations of uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), refraction, slit lamp, Schirmer Ⅰ test (SⅠT), tear film break-up time (BUT) and corneal epithelium integrity evaluation were performed 1 week, 1 month and 3 months after surgery. An intraocular pressure (IOP) examination was performed 1 week, 2 weeks, 1 month, 3 months and 4 months. The data were analyzed by repeated measures ANOVA, independent sample t-test and Mann-Whitney U test. Results: The scores for corneal irritation in the bromfenac sodium group were significantly lower than those in the fluorometholone group after surgery (Fgroups=7.8, P=0.018; Ftimes=121.7, P<0.001; Finteraction=273.4, P<0.001). At 1 month after surgery, the mean visual acuity of both groups recovered to 1.0 or better. There were no statistically significant differences in UCVA, BCVA or refraction between the two groups. At 1 month after surgery, there were 6 cases (10%) of corneal haze in the bromfenac sodium group while there were 2 cases (3%) in the fluorometholone group. The correction of IOP in the bromfenac sodium group after surgery were all below 21 mmHg, while there were 5 cases (9%) of high IOP at 2 weeks and 3 cases (5%) at 1 month in the fluorometholone group. After 3 months, both SⅠT and BUT in the two groups returned to normal levels, and the difference was not statistically significant. After 3 months, the corneal epithelium had totally recovered in most of the patients in the two groups. There was no statistically significant difference between the two groups. Conclusions: Bromfenac sodium eye drops can effectively alleviate corneal irritation after LASEK surgery. It is safe and effective for the recovery of vision and anti-inflammatory effects. Furthermore, bromfenac sodium can reduce the risk of postoperative high intraocular pressure caused by glucocorticoids. However, the incidence of corneal haze is slightly higher.
2019 Vol. 21 (7): 507-513 [Abstract] ( 415 ) [HTML 1KB] [ PDF 712KB] ( 2950 )
514 Clinical Study of Corneal Asphericity and Visual Quality after Q-Factor-Guided and Standard FS-LASIK
Xuehai Huang, Yanfeng Zhou
Objective: To compare the differences in corneal asphericity and contrast sensitivity under different conditions before and after Q-value-guided femtosecond laser in situ keratomileusis (FS-LASIK) and standard FS-LASIK for myopia, and evaluation of the efficacy of the two surgical methods for treating myopia. Methods: This was a prospective cohort study. A total of 64 moderate and low myopia patients (33 patients, 64 eyes, in the Q-guided group and 31 patients, 62 eyes, in the standard group) who were treated by FS-LASIK were selected from Laser Center, the First Affiliated Hospital of Anhui Medical University, during the same period. Visual acuity, Q-value, corneal aberration and contrast sensitivity were measured and compared before and after surgery. All the cases were followed up at 1 and 3 months. A repeated measures analysis of variance, t-test and rank sum test were used for data analysis. Results: There was no statistically significant difference for the data before surgery. The uncorrected visual acuity (UCVA) and residual refractive error of all eyes were not significantly different between the two groups after 3 months of follow-up. In the corneal 6 mm range, there was no significant difference in Q-value, spherical aberration or coma between the two groups at 3 months postoperatively. In the corneal 4.5 mm range, the Q-values and spherical aberrations of the Q-value-guided group were significantly less than that for the standard LASIK group (tSA=2.00, P=0.04; tQ=2.28, P=0.03). After surgery, contrast sensitivity in the two groups returned to preoperative levels at different spatial frequencies in various environments, and it tended to be stable at 3 months after surgery. At 3 months after surgery, the visual quality of the Q-value-guided group was better than that of the standard group under mesopic circumstances with glare (Z3 c/d=-2.0, P=0.044; Z6 c/d=-2.1, P=0.034). Conclusions: Q-value-guided LASIK for myopia and astigmatism is as safe and effective as standard FS-LASIK. Further more, Q-value-guided LASIK results in better visual quality than standard FS-LASIK under mesopic circumstances with glare.
2019 Vol. 21 (7): 514-520 [Abstract] ( 448 ) [HTML 1KB] [ PDF 706KB] ( 2824 )
521 Changes in Binocular Visual Function after SMILE
Kaixuan Du, Xiaoying Wu, Dan Wen, Bayi Xiao, Shuangzhen Liu, Yewei Yin, Chenling Li, Shengfa Hu, Yanhui Tang
Objective: To investigate the effect of small incision lenticule extraction (SMILE) on binocular visual function and its clinical significance. Methods: In this prospective clinical study, 58 myopia patients (116 eyes) who completed the SMILE surgery at the Xiangya Hospital of Central South University from March 2016 to October 2017 were selected. According to the degree of spherical equivalent (SE), patients were divided into a high myopia group (<-6.00 D) (40 eyes) and a mild-moderate myopia group (≥-6.00 D) (76 eyes). Based on the dominant eye, participants were divided into a dominant eye group (58 eyes) and a nondominant eye group (58 eyes). For all patients, accommodative and convergence function were measured before surgery and 1 week and 1 and 3 months after surgery. Repeated measures analysis of variance and independent t-tests were used to analyze and compare the data from the two groups. Results: ①The SEs of the two groups after 1 week, 1 month, and 3 months were lower than those before surgery (P<0.05). In the mild-moderate myopia group, the dominant eye amplitude of the postoperative accommodation and the positive relative accommodation were both larger than those before surgery (P<0.05). Binocular accommodative facility increased 1 month and 3 months after surgery (P<0.05). There were no statistically significant differences in similar indicators between the high myopia group at each time point before or after surgery. There was no significant difference between the mild-moderate myopia group and the high myopia group in the amplitude of accommodation of the dominant and non-dominant eyes at each time point before and after surgery. ②There was no statistically significant difference between the preoperative mild-moderate myopia group and the high myopia group in near and distance phoria, NRV/PRV, and AC/A. The postoperative near-points in the low-moderate myopia group and the high myopia group increased compared with preoperative measurements (P<0.05). Conclusions: SMILE surgery has a positive effect on accommodative and convergence function in patients with mild-moderate myopia. For patients with high myopia, changes in postoperative binocular visual function are not obvious.
2019 Vol. 21 (7): 521-526 [Abstract] ( 478 ) [HTML 1KB] [ PDF 669KB] ( 2546 )
527 The Effect of Monocular Vision Decline on Binocular Contrast Sensitivity
Silei Tan, Jiemin Chen, Meng Wang, Xiaoying Yu, Yiyang Lei, Weiyi Tang, Wentao Xia
Objective: To study the changes in binocular contrast sensitivity (CS) when monocular vision declines, and to explore the effects of monocular vision decline on binocular function and interaction, and to explore the value of judicial appraisal. Methods: In this experimental study, 46 normal subjects (24 males and 22 females) were enrolled in Academy of Forensic Science from March 2016 to August 2017. Monocular visual acuity of them could be corrected to more than 4.9. Experimental lenses were placed in front of the dominant eyes to induce experimental monocular visual impairment in varying degrees. Visual acuity and CS for monocular and binocular function were measured. Binocular summation ratios (BSR) were calculated, further spherical tests, analysis of variance and the Kruskal-Wallis test. Results: Decreased monocular vision can cause a certain decrease in binocular vision, but binocular vision is still better than monocular vision. When visual acuity declined to the level of mild damage, the normal inverted U-shaped curve of the whole frequency band was destroyed, and visual acuity had a more obvious decline at medium and high spatial frequencies than at low spatial frequencies. At high frequencies and normal visual acuity in both eyes, the maximum sum of both eyes appeared (BSR=1.48). When monocular visual acuity gradually declined, the binocular average and inhibition appeared (BSR<1). There was a certain degree of tolerance and spatial dependence with binocular interaction. Conclusions: Decreased monocular vision has a certain influence on binocular CS and the form and degree of binocular interaction. A binocular CS test can reflect the degree of monocular vision loss. It has practical value and is worthy of clinical application and judicial expertise.
2019 Vol. 21 (7): 527-533 [Abstract] ( 501 ) [HTML 1KB] [ PDF 815KB] ( 2884 )
534 Retrospective Analysis of Factors Affecting Abnormal Vault after ICL Implantation
Tongfeng Cui, Jin Zhou, Zheng Wang
Objective: To analyze the factors that may lead to an abnormal vault after implantation of the implantable collamer lens (ICL). Methods: This research was based on the retrospective analysis of sixty patients (67 eyes) who underwent ICL V4c replacement after collamer lens implantation with a V4c lens in the Chengdu Aier Eye Hospital between November 2014 and November 2017. The replacement was performed because of abnormal vaults of the initial lens implantations, either less than 250 μm or more than 750 μm. Seventy patients (70 eyes) were randomly chosen as the control group from those who underwent ICL implantation during the same period and had normal vaults (250 to 750 μm). Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), manifest refraction, intraocular pressure (IOP), corneal endothelial cell density (ECD), and lens thickness (LT) were measured before surgery. The posterior chamber angle, height of the ciliary processes (T value), sulcus-to-sulcus (STS) horizontal distance, STS vertical distance, and anterior chamber depth (ACD) were measured by an ultrasound biomicroscope (UBM). All patients were followed more than 6 months. UCVA, manifest refraction, BCVA, IOP, ECD, and vault height were measured. Data were analyzed using a t-test and multiple linear regression. Results: There were significant differences between the high vault group and the low vault group for posterior chamber angle and ICL size and ACD (all P<0.001). There were significant differences between the high vault group and normal vault group for ICL size and posterior chamber angle. Posterior chamber angle, ICL size, STS horizontal distance, T value, ACD, and LT were statistically significant factors for the abnormal vault (adjusted, R2=0.608, F=5.84, P<0.001). Eight eyes had a vault less than 250 μm after implantable collamer lens replacement in the low vault group. Whereas the vault was normal after ICL replacement in all eyes of the high vault group. There were no serious complications such as anterior subcapsular cataract, high intraocular pressure, or corneal endothelial decompensation during the observation period. Conclusions: Multiple ciliary sulcus factors affect vault after ICL implantation. T value, posterior chamber angle, STS horizontal distance, ACD, ICL size, and LT may be related to an abnormal vault. For cases where abnormal vault may occur, the ICL size can be determined in conjunction with the posterior angle to help achieve a proper vault.
2019 Vol. 21 (7): 534-539 [Abstract] ( 415 ) [HTML 1KB] [ PDF 677KB] ( 4287 )
540 Oral Azithromycin for the Treatment of Moderate to Severe Meibomian Gland Dysfunction
Hongjuan Wang, Yingying Gao, Xiulan Li
Objective: To observe the clinical efficacy of oral azithromycin in patients with moderate to severe meibomian gland dysfunction (MGD), and the structural changes in meibomian glands. Methods: This was a prospective clinical study. Forty-nine patients (98 eyes) who had moderate to severe MGD were recruited in the Second Affiliated Hospital, Fujian Medical University, from April 2016 to January 2017. All patients underwent comprehensive ocular surface examination and slit lamp examination and were divided into two groups: 26 patients in the observation group and 23 patients in the control group. The observation group was given artificial tears and oral azithromycin 500 mg once daily for 3 days, then stopped for 7 days. There were 10 days in a treatment cycle with a total of three cycles for the treatment.The control group received only artificial tear treatment. All patients underwent modified meibomian gland compression during the first visit and for each follow-up, all of which were combined with eyelid hot compress and blepharospasm cleaning. Then an ocular check-up was performed, including the following aspects: Ocular surface disease index (OSDI), noninvasive first break-up time (NIF-BUT), noninvasive average break-up time (NIAvg-BUT), tear meniscus height (TMH), R-scan, loss rate of the meibomian gland, assessment of meibomian gland orifices, meibum quality score, meibum expression score, fluorescein stain test (FL), and Schirmer Ⅰ test (SⅠT) between pre-therapy and post-treatment. Data were analyzed by an independent samples t test, Mann-Whitney U test, paired t test and Wilcoxon paired rank sum test. Results: After treatment, the assessment of meibomian gland orifices (Z=-3.093), meibum quality score (Z=-2.501), meibum expression score (Z=-3.175) as well as FL (Z=-2.602) of the control group were improved compared with those before treatment, with statistically significant differences (P<0.05). However, there were no statistically significant differences in other indexes in the control group. After treatment, the OSDI (t=6.174), loss rate of the meibomian gland (t=2.402), assessment of meibomian gland orifices (Z=-5.192), meibum quality score (Z=-5.073), meibum expression score (Z=-4.807), and FL (Z=-3.587) of the observation group were improved compared with those before treatment, with statistically significant differences (P<0.05). There were no statistically significant differences in other indexes in the observation group. Statistically significant differences were observed in OSDI (t=-3.778), NIAvg-BUT (Z=-2.043), loss rate of the meibomian gland (t=-2.123), assessment of meibomian gland orifices (Z=-6.318), meibum quality score (Z=-5.852), meibum expression score (Z=-3.951) and SⅠT (Z=-2.462) between the two groups after treatment (P<0.05) and the observation group improved more obviously, but no statistically significant differences in other indexes after treatment. Conclusions: Oral azithromycin can be used to treat patients with moderate to severe MGD, relieve symptoms and partially regain the function of the meibomian gland.
2019 Vol. 21 (7): 540-548 [Abstract] ( 419 ) [HTML 1KB] [ PDF 5893KB] ( 2967 )
549 Early Changes in Astigmatism after Correction of Senile Upper Eyelid Skin Laxity
Renhui Dou, Shumei Wen, Xiaoyu Yu, Haochen Guo, Hengli Lian
Objective: To investigate the early changes in ocular refraction after correction of upper eyelid skin laxity. Methods: This was a prospective case-control study. Patients with senile upper eyelid skin laxity were recruited from the Eye Hospital of Wenzhou Medical University at Hangzhou from July 2016 to December 2017. Sixty-two patients were divided into two groups: 40 patients (80 eyes) who underwent surgery were included in the treatment group, 22 patients (44 eyes) who declined surgery were included in the control group. The treatment group was examined preoperatively and 3 months postoperatively. The control group was initially examined and then re-examined 3 months later. The best corrected visual acuity, refractive errors, corneal curvature and central corneal thickness were analyzed. Paired t tests or rank sum tests were used to compare the differences within a groups, covariance analysis was used to compare the differences between the groups. Results: In the treatment group, astigmatism decreased after surgery; the mean change was 0.17 D (t=-3.31, P<0.001). There were no significant differences in corrected visual acuity, spherical equivalent diopter, corneal curvature or corneal thickness before and after surgery. There were no statistical differences in the control group when testing results were compared. There was a significant difference in astigmatism between the two groups (F=13.672, P<0.001), but no statistical differences in corrected visual acuity, spherical equivalent diopter, corneal curvature or corneal thickness. Conclusions: Astigmatism decreased early after surgical correction, but the astigmatic axis had no significant change.
2019 Vol. 21 (7): 549-552 [Abstract] ( 401 ) [HTML 1KB] [ PDF 678KB] ( 2470 )
Case Report
553
2019 Vol. 21 (7): 553-556 [Abstract] ( 382 ) [HTML 1KB] [ PDF 12265KB] ( 2073 )
Review
557 The Application of Optical Coherence Tomography Angiography in Glaucoma
Linhong Ye, Qing Yuan, Yi Shao
Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging system, can produce the structure data of retina and choroid, shows the structure and blood flow information. Split-spectrum amplitude-decorrelation angiography (SSADA) algorithman (an important part of OCTA) can help reduce the signal-to-noise ratio, enhancing visualization of retinal vasculature using motion contrast. OCTA can provide more meaningful image data for the treatment which is a major breakthrough in the eye detection method. Currently there is lack of effective early diagnosis methods for glaucoma. OCTA as a parameter, can evaluate the structural parameters of glaucoma. This article will review the application of this new non-invasive method in the clinical application of three types of glaucoma: Angle-closure glaucoma, open angle glaucoma and normal tension glaucoma.
2019 Vol. 21 (7): 557-560 [Abstract] ( 434 ) [HTML 1KB] [ PDF 644KB] ( 2748 )
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