Objective: To explore the information management methods for eye and vision care of children and to create and apply the information system for improvement of children's eye and vision care in the Huzhou municipal area. Methods: Using “the technical specification for eye and vision care for children” as a standard reference, an eye and vision care module was added to the health information system for children.A database was created, and relevant information was collected, curated, and monitored in real time by the children's health care provider at the city, county and township level. Results: After the creation of the information system for children's eye and vision care, and on the basis of the initial trial at 9 suitable sites at the city, county, and town levels, the system was then expanded to 112 work stations across the whole municipal area. Four thousand entries were entered into the system. The new management system had significantly improved the quality of health care, and increased the screening rate for children's eye diseases. This information system also benefited the establishment of the children's eye care archives and the collection and analysis of statistical information of children's eye disease. Conclusions: The creation of the information system improved the management for children's eye and vision care. It can also provided scientific evidence for policy evaluation and revision at the decision-making level. Further development of the children's eye and vision care management system will inevitably lead to better analysis of childhood eye diseases and improved medical care.