Objective: To study the changes in accommodative response and microfluctuations in patients with intermittent exotropia (IXT) before and after surgery. Methods: Twenty-nine patients 8-20 years of age with IXT were recruited for a prospective clinical study at Eye Hospital of Wenzhou Medical University from June to August 2017. A Grand Seiko WAM-5500 auto-refractor was used to measure the accommodative response and microfluctuations at 33 cm before and after strabotomy. Data were analyzed using a paired t-test. results: Before surgery, the accommodative response in IXT patients was higher under binocular conditions (dominant eye: 2.23±0.44 D; nondominant eye: 2.44±0.51 D) compared to monocular conditions (2.03±0.40 D; 2.11±0.40 D)(t=2.481, P=0.019; t=2.786, P=0.009). After surgery, the accommodative response under binocular conditions (after surgery: 2.00±0.37 D; 2.11±0.50 D; t=2.628,P=0.014; t=3.120, P=0.004) decreased and accommodative microfluctuations in IXT patients under binocular conditions also decreased (before surgery: 0.22±0.14 D, 0.22±0.12 D; after surgery: 0.16±0.08 D,0.16±0.07 D; t=2.306, P=0.029; t=2.242, P=0.033). conclusions: After surgery, the accommodative ability of IXT patients improves, more stable accommodative microfluctuations and visual performance improved.
高帆,保金华,张芳,陈浩. 间歇性外斜视手术对调节反应及调节微波动的影响[J]. 中华眼视光学与视觉科学杂志, 2018, 20(9): 536-540.
Fan Gao,Jinhua Bao,Fang Zhang,Hao Chen . The Impact of Surgery for Intermittent Exotropia on Accommodative Response and Microfluctuation. Chinese Journal of Optometry Ophthalmology and Visual science, 2018, 20(9): 536-540. DOI: 10.3760/cma.j.issn.1674-845X.2018.09.005
Somer D, Demirci S, Çinar FG, et al. Accommodative ability in exotropia: Predictive value of surgical success. J AAPOS, 2007,11(5): 460-464. DOI: 10.1016/j.jaapos.2007.01.123.
[4]
Abroms AD, Mohney BG, Rush DP, et al. Timely surgery in intermittent and constant exotropia for superior sensory outcome. Am J Ophthalmol, 2001, 131(1): 111-116. DOI: 10.1016/
Le R, Bao J, Chen D, et al. The effect of blur adaptation on accommodative response and pupil size during reading. J Vis,2010, 10(14): 1-12. DOI: 10.1167/10.14.1.
Lin H, Drobe B, Jin W, et al. Effects of near addition lenses and prisms on accommodative microfluctuations in Chinese children. Optom Vis Sci, 2016, 93(5): 488-496. DOI: 10.1097/OPX.0000000000000816.
Subbaram MV, Bullimore MA. Visual acuity and the accuracy of the accommodative response. Ophthalmic Physiol Opt, 2002,22(4): 312-318. DOI: 10.1046/j.1475-1313.2002.00037.x.
[16]
Anderson HA, Glasser A, Stuebing KK, et al. Minus lens stimulated accommodative lag as a function of age. Optom Vis Sci, 2009, 86(6): 685-694. DOI: 10.1097/OPX.0b013e3181a7294f.
[5]
杨景存. 眼外肌病学. 郑州: 郑州大学出版社, 2003: 75-76.
[17]
Heron G, Charman WN, Gray LS. Accommodation responses and ageing. Invest Ophthalmol Vis Sci, 1999, 40(12): 2872-2883.
[18]
Hasebe S, Nonaka F, Ohtsuki H. Accuracy of accommodation in heterophoric patients: Testing an interaction model in a large clinical sample. Ophthalmic Physiol Opt, 2005, 25(6): 582-591.DOI: 10.1111/j.1475-1313.2005.00331.x.
[19]
Goss DA, Rainey BB. Relationship of accommodative response and near point phoria in a sample of myopic children. Optom Vis Sci, 1999, 76(5): 292-294. DOI: 10.1097/00006324-199905000-00016.
[20]
Tassinari JT. Monocular estimate method retinoscopy: Central tendency measures and relationship to refractive status and heterophoria. Optom Vis Sci, 2002, 79(11): 708-714. DOI:10.1097/00006324-200211000-00008.
Le R, Bao J, Chen D, et al. The effect of blur adaptation on accommodative response and pupil size during reading. J Vis,2010, 10(14): 1-12. DOI: 10.1167/10.14.1.
Lin H, Drobe B, Jin W, et al. Effects of near addition lenses and prisms on accommodative microfluctuations in Chinese children. Optom Vis Sci, 2016, 93(5): 488-496. DOI: 10.1097/OPX.0000000000000816.
Subbaram MV, Bullimore MA. Visual acuity and the accuracy of the accommodative response. Ophthalmic Physiol Opt, 2002,22(4): 312-318. DOI: 10.1046/j.1475-1313.2002.00037.x.
[16]
Anderson HA, Glasser A, Stuebing KK, et al. Minus lens stimulated accommodative lag as a function of age. Optom Vis Sci, 2009, 86(6): 685-694. DOI: 10.1097/OPX.0b013e3181a7294f.
[21]
Scheiman M, Wick B. Clinical management of binocuuclar vision: hetereophoric, accommodative and eye movement disorders.3rd ed. Lippincott: Williams & Wilkins, 2008: 59-64,
[17]
Heron G, Charman WN, Gray LS. Accommodation responses and ageing. Invest Ophthalmol Vis Sci, 1999, 40(12): 2872-2883.
[18]
Hasebe S, Nonaka F, Ohtsuki H. Accuracy of accommodation in heterophoric patients: Testing an interaction model in a large clinical sample. Ophthalmic Physiol Opt, 2005, 25(6): 582-591.DOI: 10.1111/j.1475-1313.2005.00331.x.
[19]
Goss DA, Rainey BB. Relationship of accommodative response and near point phoria in a sample of myopic children. Optom Vis Sci, 1999, 76(5): 292-294. DOI: 10.1097/00006324-199905000-00016.
[20]
Tassinari JT. Monocular estimate method retinoscopy: Central tendency measures and relationship to refractive status and heterophoria. Optom Vis Sci, 2002, 79(11): 708-714. DOI:10.1097/00006324-200211000-00008.
12
1-123.
[22]
Ha SG, Jang SM, Cho YA, et al. Clinical exhibition of increased accommodative loads for binocular fusion in patients with basic intermittent exotropia. BMC Ophthalmol, 2016, 16(1): 1-6. DOI:10.1186/s12886-016-0260-y.
[23]
Sharma P, Saxena R, Narvekar M, et al. Evaluation of distance and near stereoacuity and fusional vergence in intermittent exotropia. Indian J Ophthalmol, 2008, 56(2): 121-125. DOI: 10.4103/0301-4738.39116.
[24]
Van Der Heijde GL, Beers APA, Dubbelman M. Microf luctuations of steady-state accommodation measured with ultrasonography.Ophthalmic Physiol Opt, 1996, 16(3): 216-221. DOI: 10.1016/0275-5408(95)00051-8.
[25]
Xu J, Zheng Z, Drobe B, et al. The effects of spatial frequency on the accommodation responses of myopes and emmetropes under various detection demands. Vision Res, 2015, 115(Pt A):1-7. DOI: 10.1016/j.visres.2015.05.020.
[26]
Charman WN, Heron G. Fluctuations in accommodation: a review. Ophthalmic Physiol Opt, 1988, 8(2): 153-164. DOI:10.1111/j.1475-1313.1988.tb01031.x.
[27]
Day M, Strang NC, Seidel D, et al. Refractive group differences in accommodation microfluctuations with changing accommodation stimulus. Ophthalmic Physiol Opt, 2006, 26(1): 88-96. DOI:10.1111/j.1475-1313.2005.00347.x.
[21]
Scheiman M, Wick B. Clinical management of binocuuclar vision: hetereophoric, accommodative and eye movement disorders.3rd ed. Lippincott: Williams & Wilkins, 2008: 59-64,
12
1-123.
[22]
Ha SG, Jang SM, Cho YA, et al. Clinical exhibition of increased accommodative loads for binocular fusion in patients with basic intermittent exotropia. BMC Ophthalmol, 2016, 16(1): 1-6. DOI:10.1186/s12886-016-0260-y.
[23]
Sharma P, Saxena R, Narvekar M, et al. Evaluation of distance and near stereoacuity and fusional vergence in intermittent exotropia. Indian J Ophthalmol, 2008, 56(2): 121-125. DOI: 10.4103/0301-4738.39116.
[24]
Van Der Heijde GL, Beers APA, Dubbelman M. Microf luctuations of steady-state accommodation measured with ultrasonography.Ophthalmic Physiol Opt, 1996, 16(3): 216-221. DOI: 10.1016/0275-5408(95)00051-8.
[25]
Xu J, Zheng Z, Drobe B, et al. The effects of spatial frequency on the accommodation responses of myopes and emmetropes under various detection demands. Vision Res, 2015, 115(Pt A):1-7. DOI: 10.1016/j.visres.2015.05.020.
[26]
Charman WN, Heron G. Fluctuations in accommodation: a review. Ophthalmic Physiol Opt, 1988, 8(2): 153-164. DOI:10.1111/j.1475-1313.1988.tb01031.x.
[27]
Day M, Strang NC, Seidel D, et al. Refractive group differences in accommodation microfluctuations with changing accommodation stimulus. Ophthalmic Physiol Opt, 2006, 26(1): 88-96. DOI:10.1111/j.1475-1313.2005.00347.x.