Objective To investigate the effect of posterior scleral reinforcement in eyes with pathological myopic macular retinoschisis. To observe macular retinoschisis and ERG changing. Methods Retrospective study. Thirty-two eyes of 25 patients with pathological myopic macular retinoschisis （6 eyes of foveal detachment） who underwent surgery with the posterior scleral reinforcement were studied. The best corrected visual acuity， spherical equivalent， axial length， OCT and ERG outcomes were observed before and 6 months after surgery. Paired t test was used to evaluate best corrected visual acuity， spherical equivalent and axial length between preoperation and postoperation. Wilcoxon test was used to compare the value of macular splitting cavity and the parameters of ERG. Results There were significant differences in mean spherical equivalent and mean axial length between pre- and postoperation （t=-11.23， 13.23， P<0.05）. OCT showed： healing of macular retinoschisis in 14 eyes， max value of macular splitting cavity preoperation was 277（190-428）μm； improved macular retinoschisis in 17 eyes， max value of macular splitting cavity changed significantly（Z=-3.724， P<0.01） from a preoperative value of 447（344-617）μm to 194（106-259）μm at 6 months postoperation； no change in 1 eye. ERG： healing group（14 eyes）， the max-a wave showed a significant change between preoperative and postoperative from 114（63.45-143.00）μV to 119（93.75-169.50）μV， respectively （Z=-2.232， P<0.05）； improved group （17 eyes）， the max-a wave showed a significant change between preoperative and postoperative from 104（76.65-130.00）μV to 107（83-151）μV， respectively （Z=-2.056， P<0.05）. There were no significant changes between other parameters. No serious complications were observed. Conclusion Posterior scleral reinforcement is an approach to treat pathological myopic macular retinoschisis， not only help to reduce macular splitting cavity， but also improve retina photoreceptor conduction function.