Comparisons of Multifocal Electroretinograms and Optical Coherence Tomography Images before and after Surgery in Patients with Rhegmatogenous Retinal Detachment Involving the Macular Area
Ruizhen Cai,Kang Chen
Henan Eye Institute, Henan Eye Hospital, Zhengzhou 450003, China
Objective: To evaluate changes in multifocal electroretinogram (mfERG) and optical coherence tomography(OCT) before and after surgery in patients with thegmatogenous retinal detachment (RRD) involving the macular area. Methods: This was a retrospective study in which 52 eyes (52 patients) with RRD involving
the macular area (RRD group) were compared with the fellow healthy eyes (normal control group). All patients in the RRD group underwent scleral buckling surgery. Before each surgery, the eyes were examined by mfERG and OCT. At one week and at l. 3, and 6 months after surgery, the eyes were examined again.
Using Pearson product moment correlation analysis and repeated measurement methods were used to analyze the datas. Results: A11 RRD eyes successfully underwent the surgery successfully. The thickness of the macular fovea of the RRD group before surgery, 534士44 Um, was significantly greater than for the
normal control group(户17.127, P<0.05). At one week and at l, 3. and 6 months after surgery, the foveal retinal thickness decreased significantly (P<O.01). The Nl and Pl wave amplitude densities at ring l of the RRD eyes were significantly less than in the control eyes (tN l =17.372, tPl=23.943, P<0.05) as was the delay
in the peak latency (tNl=5.291, tPl=7.306, P<0.05). At one week and at l, 3, and 6 months after surgery, the N1 and Plwave amplitude densities at ring l were higher than before the surgery (P<O.01). The delay in the peak latency was not significantly changed compared to the preoperative values. At l, 3, and 6 months
after the surgery, the best corrected visual acuity was negatively correlated with macular center thickness(r=-0.801, -0.695, -0.643, P<0.05, at each follow up). The ring l Nl and Pl wave amplitude densities were positively correlated with the macular center thickness (rx11=0.702, 0.695, 0.632, rpl=0.811, 0.713, 0.648,
P<0.05, at each follow up), but the peak latency was not correlated with the macular center thickness.Conclusions: The morphology and function in the macular area of patients with RRD can be objectively and comprehensively measured by OCT and mfERG applications. With mfERG and OCT. the success after
retinal detachment surgery can be assessed.
蔡瑞珍,陈慷. 累及黄斑的孔源性视网膜脱离手术前后黄斑区光学相干断层扫描与多焦视网膜电图的变化[J]. 中华眼视光学与视觉科学杂志, 2017, 19(9): 554-559.
Ruizhen Cai,Kang Chen. Comparisons of Multifocal Electroretinograms and Optical Coherence Tomography Images before and after Surgery in Patients with Rhegmatogenous Retinal Detachment Involving the Macular Area. Chinese Journal of Optometry Ophthalmology and Visual science, 2017, 19(9): 554-559. DOI: 10.3760/cma.j.issn.1674-845X.2017.09.007
Sutter EE, Tran D.The field topography of ERG components in man--l. The photopic luminance response. Vision Res, 1992, 32
[2]
Sutter EE, Tran D.The field topography of ERG components in man--l. The photopic luminance response. Vision Res, 1992, 32
(3)
: 433-446.
(3)
: 433-446.
[3]
吴乐正,临床多焦视觉电生理学,北京:北京科学技术出版社,2004: 54
[3]
吴乐正,临床多焦视觉电生理学,北京:北京科学技术出版社,2004: 54
[4]
Thelen U. Amler S, Osada N, et al. Outcome of surgery after macula-off retinal detachment-results from MUSTARD. one of
the largest databases on buckling surgery in Europe. Acta Ophthalmol,2012, 90(5): 481-486. DOI: 10.1111/j .1755-3 768 .2010.01939.x.
[5]
Salicone A, Smiddy WE, Venkatraman A, et al . Visual recovery after scleral buckling procedure for retinal detachment.
Ophthalmology, 2006, 113(10) : 1734-1742.
[6]
Hassan TS. Sarrafizadeh R, Ruby AJ, et al. The effect of duration of macular detachment on results after the scleral buckle repair of primary, macula-off retinal detachments. Ophthalmology,2002, 109(1): 146-152.
Wolfensberger TJ. Foveal reattachment after macula-off retinal detachment occurs faster after vitrectomy than after buckle surgery.Ophthalmology, 2004, 111(7): 1340-1343. DOl: 10.1016/j.ophtha.2003.12.049.
[11]
Hagimura N, Iida T. Suto K. et al. Persistent foveal retinal detachment after successful thegmatogenous retinal detachment surgery. Am J Ophthalmol, 2002, 133(4): 516-520.
[12]
Wakabayashi T, Oshima Y, Fujimoto H, et al. Foveal microstructure and visual acuity afier retinal detachment repair: imaging analysis by Fourier-domain optical coherence tomogiaphy. Ophthalmology,2009, 116(3): 519-528. DOl: 10.1016/j.ophtha.2008.10.001.
[13]
Seo JH, Woo SJ, Park KH, et al. Influence of persistent submacular fluid on visual outcome after successful scleral
buckle surgery for macula-off retinal detachment. Am J Ophthalmol. 2008, 145(5): 915-922. DOI: 10.1016/j.ajo.2008.01.005.
[14]
Moschos M, Apostolopoulos M, Ladas J, et al. Assessment of macular function by multifocal electroretinogram before and
after epimacular membrane surgery. Retina, 2001, 21(6) : 590-595.
Theodossiadis G,Theodossiadis P, Malias J, et al.Preoperative and postoperative assessment by multifocal electroretinography in the management of optic disc pits with serous macular detachment. Ophthalmology, 2002, 109(12): 2295-2302.
[17]
Kondo M, Miyake Y,Horiguchi M, et al. C1inic evaluation of multifocal electroretinogram. Invest ophthalmol Vis Sic, 1995,36: 2146