Objective To investigate the clinical results of 23-G minimally invasive vitrectomy combined with chandelier illumination for treatment of superior bullous rhegmatogenous retinal detachment (SBRRD),and to analyze the intraoperative and postoperative complications.Methods In a retrospective case series study,50 eyes of 50 consecutive patients with SBRRD were analyzed.For all cases,a 23-G three-port vitrectomy system with a two-step incision was used,inserting the chandelier lighting probe at six o'clock via the pars plana with the help of a noncontact panoramic viewing system,23-G vitrectomy with endolaser photocoagulation and C3F8 tamponade.Postoperative follow-up ranged from 5 to 49 months (mean 23.9±1.3 months).Main outcome measures included complications from the operation,postoperative inflammatory reaction,retinal anatomical status,and best corrected visual acuity (BCVA).Results Intraoperative suture placement was required for leaking selerotomies in 17 cases (34％).No iatrogenic retinal breaks or hemorrhage occurred during the operations.The results showed only mild signs of postoperative inflammatory reaction.One patient (2％) had hypotony on postoperative day 1.Early ocular hypertension in 16 eyes (32％) was controlled by hypotensive treatment in four days.No choroidal detachment,hyphema,effusion or endophthalmitis occurred.All congestion cleared up after 2 weeks.The primary anatomical success rate was 98％;the final retinal reattachment rate was 100％.For the off-macular cases,BCVA improved from the preoperative mean of 2.82±0.69 to the postoperative mean of 4,34±0.49,and the difference was statistically significant (t=13.72,P＜0.01).For the on-macular cases,BCVA improved from the preoperative mean of 4.61±0.19 to the postoperative mean of 4.70±0.19 but the difference was not statistically significant (t=2.20,P=0.064).Postoperative cataract progression occurred in 7 eyes (14％).Conclusion The 23-G minimally invasive vitrectomy combined with chandelier illumination is a safe and effective therapeutic method for superior bullous rhegmatogenous retinal detachment.