Abstract：Objective: To investigate the distribution characteristics and related factors of macular thickness in children and teenagers with healthy eyes. Methods: This descriptive study included 284 children and teenagers (568 normal eyes) with a mean age of 10.1±2.8 years, range 4-17 years, and a refractive diopter range of -8- +6 D who were seen at the Department of Ophthalmology, Kunming Children's Hospital from July 2014 to August 2016. Macular thickness was measured by optical coherence tomography (OCT), 6 mm diameters that included 9 areas (A1-A9). Eyes were divided into different groups based on sex,left and right eyes, age (≤10 years and >10 years, two groups), and spherical equivalent (myopia: SE≤ -0.50 D; emmetropia: -0.50 D10 years of age groups except for zones A1 of the left eyes and A1, A2 of the right eyes (t=3.322, P=0.001; t=3.240, P=0.001; t=2.274, P=0.024). In the comparison of different dioptric groups, the hyperopia group had the thickest macula and the myopia group had the thinnest except for zones A6, A8, A9. There was no statistically significant difference in other zones between the three groups. Conclusions: The thickness mapping of the macula demonstrates that macular thickness is not evenly distributed across the 6 mm diameters. The macular averages at the central zone (diameter: 1.0 mm) are the thinnest and the thickest are at the paracentral zone (diameter: 1.0-3.0 mm). No correlations were found between macular thickness and age or sex. The central zone macular thickness tends to thin with age. The macula is thickest in the hyperopia group and is thinnest in the myopia group in the superior, inferior, and temporal areas of the peripheral zones.
吴斯琪 肖亦爽. 正常儿童青少年黄斑厚度的分布及相关影响因素[J]. 中华眼视光学与视觉科学杂志, 2020, 22(2): 124-129.
Siqi Wu, Yishuang Xiao. Distribution Characteristics and Related Factors of Macular Thickness in Children and Teenagers with Normal Eyes. Chinese Journal of Optometry Ophthalmology and Visual science, 2020, 22(2): 124-129. DOI: 10.3760/cma.j.issn.1674-845X.2020.02.008
Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science, 1991, 254(5035): 1178-1181. DOI: 10.1126/science.1957169.
[3]
Costa RA, Skaf M, Melo LA, et al. Retinal assessment using optical coherence tomography. Pro Retin Eye Res, 2006, 25(3): 325-353. DOI: 10.1016/j.preteyeres.2006.03.001.
[4]
Morgan IG, Rose KA, Ellwein LB. Isemmetropia the natural endpoint for human refractive development? An analysis of population-based data from the refractive error study in children (RESC). Acta Ophthalmol, 2010, 88(8): 877-884. DOI: 10.1111/j.1755-3768.2009.01800.x.
[5]
Huynh SC, Wang XY, Rochtchina E, et al. Distribution of macular thickness by optical coherence tomography: Findings from a population-based study of 6-year-old children. Invest Ophthalmol Vis Sci, 2006, 47(6): 2351-2357. DOI: 10.1167/ iovs.05-1396.
[6]
Huang J, Liu X, Wu Z, et al. Macular and retinal nerve fiber layer thickness measurements in normal eyes with the Stratus OCT, the Cirrus HD-OCT, and the Topcon 3D OCT-1000. J Glaucoma, 2011, 20(2): 118-125. DOI: 10.1097/IJG.0b013e3181d786f8.
Kee SY, Lee SY, Lee YC. Thicknesses of the fovea and retinal nerve fiber layer in amblyopic and normal eyes in children. Korean J Ophthalmol, 2006, 20(3): 177-181. DOI: 10.3341/ kjo.2006.20.3.177.
[11]
Zhale R, Hamideh S, Narges B, et al. Macular thickness in moderate to severe amblyopia. Korean J Ophthalmol, 2018, 32(4): 312-318. DOI: 10.3341/kjo.2017.0101.
浙公网安备 33030202001892号