Objective To evaluate the therapeutic effect of the bandage contact lens （BCL） using ultra-high resolution optical coherence tomography （UHR-OCT） after pterygium surgery. Methods Prospective case-control study. Sixty eyes of 60 patients undergoing pterygium excision and conjunctival autografting were randomly allocated into 2 groups： 30 eyes were covered with silicone hydrogel BCLs at the conclusion of surgery and 30 eyes served as a control. UHR-OCT scans of the cornea were performed sequentially on day 1， day 2， day 3， and then every other day until the end of re-epithelialization after surgery. Complete corneal epithelial healing was verified with fluorescein staining after removal of the BCLs. Post-surgical pain was evaluated using the visual analogue scale （VAS）. An independent t test and a Mann-Whitney U test were used. Results All BCLs were successfully fit without any contact lens-related complications. UHR-OCT images clearly revealed the architectural features of the postoperative cornea with BCL in situ and showed the epithelial healing process. UHR-OCT imaging highly agreed with the fluorescein staining in detecting corneal epithelial defects （95%）. Based on the assessment by UHR-OCT， the average time line for re-epithelialization in the BCL group was 3.7±1.2 days while in the control group it was 4.8±1.5 days （t=16.78， P<0.01）. VAS scores reported lower pain levels in the BCL group compared to the control group at each time point （Z=-4.75， -3.84， -2.96， -2.52， -1.98， all P<0.05）. Conclusion Silicone hydrogel BCL is recommended as an adjuvant therapy after pterygium surgery for its efficacy in improving re-epithelialization and postoperative comfort. UHR-OCT is an excellent tool in monitoring corneal epithelial healing under BCLs and determining the appropriate time for lens removal.
陈鼎,连燕,黄芳,等. 超高分辨率眼前节OCT评价翼状胬肉术后绷带式角膜接触镜的治疗效果. 中华眼视光学与视觉科学杂志, 2014, 16(3):150-154. DOI:10.3760/cma.j.issn.1674-845X.2014.03.006.
Chen Ding,Lian Yan,Huang Fang,et al. An evaluation of the therapeutic effect of the bandage contact lenses after pterygium surgery using ultra-high resolution optical coherence tomography. Chinese Journal of Optometry Ophthalmology and Visual Science, 2014, 16(3):150-154.
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